93.8%
report reduced or eliminated Brain Fog
96.2%
claim improved memory, faster word recall and sharper thinking
98.4%
trust & recommend Pure Neuro to close family and friends
⭐️⭐️⭐️⭐️⭐️ 4.8/5 Trusted by 434,000 customers
Pure Neuro
World’s only 100% natural & premium brain supplement backed by 70+ randomized controlled trials involving 500,000+ real people
✔️ 28% sharper memory recall of names, words, and faces1, 2
✔️ 16x long-term memory storage through synaptic memory protein activation3
✔️ 6X mental processing speed for less confusion, hesitation, or losing your train of thought4
✔️ 6+ brain pathways optimized
✔️ 100% natural brain health support
✔️ Feel like the sharpest version of YOU again
Scientifically formulated by
Dr. Anthony Capasso
MD, ABIM board certified integrative medicine specialist
25 years practicing & globally renowned expert in preventative medicine, age management, and bioidentical hormone science.
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Verified Buyer
"I'm almost 80 and still working as a CPA. Pure Neuro keeps me sharp." - C. Rodriguez
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"Studying tech communications at 72 and competitive with students 18 years of age" - Eva M.
Supplement Facts
Benefits
PureNeuro starts working in 24 hours. Customers describe it as "the brain fog lifting".
With continued use, you'll feel sharper in all areas of cognitive function, including memory recall, focus & clarity.
You'll find it easier to keep up in fast-paced conversations, learn new things, and stay sharp at work...as your brain naturally begins to process information at high speeds.
Ingredients & Allergy Advice
PureNeuro is 100% Natural. Contains NO soy, dairy or gluten. Non GMO. NO fillers, additives, artificial colors or preservatives. Third party tested for purity and held to the highest quality manufacturing standards in the USA.
How to Take
It's easy! Take 2 capsules per day, with a glass of water. Take them morning or night. With or without food.
Proudly Serving 434,000+ People & Their Loved Ones
Feel Like The Sharpest Version Of YOU Again
Active 6+ Brain Pathways With 1 Convenient Capsule
Backed By Research Involving 500,000+ Human Participants & 70+ Randomized Controlled Trials
while the 12 most popular brain supplements sold in the USA were tested on only a few hundred people.
Performance
Stay razor sharp as you age with premium-grade, research-backed ingredients proven to support focus, memory & clarity
Long-Range Brain Health
World’s only brain supplement on the planet clinically proven to naturally defend against memory-loss proteins amyloid-beta & tau
Activates 6+ Biological Brain Pathways
providing holistic cognitive support for people of all ages, body types, lifestyles & genetics
Caffeine & Stimulant Free
while 89% of brain supplements contain stimulants that cause jitters & energy crashes
100% Natural Formula Designed by Leading Longevity Doctor
Dr. Anthony Capasso, who carefully crafted this precision formula over 25+ years of clinical practice
16X
Increase in Arc Synaptic Memory Protein, essential long term memory
28%
Improvement in memory recall
2.5X
Increase in brain growth factor (BDNF) within 60 mins
2.8x
Improvement in verbal memory compared to placebo7
6X
Improvement in processing speed compared to placebo
28.3%
Reduction in mental fatigue
51.6%
Meaningfully Improved their sense of well-being
What’s Inside?
PureNeuro’s precision formula is crafted with 100% natural, premium-grade ingredients backed by decades of clinical human trials and 25+ years of real biomedical practice by Dr. Anthony Capasso. Every ingredient is sourced to the highest quality standards & rigorously third-party tested for purity before it ever makes it in the bottle.
Brazilian Green Propolis
Gently breaks down “brain plaque” (amyloid-beta & tau accumulation) unlocking the brain's ability to form and store memories.
✅ 2.8x improvement in verbal memory compare to placebo11
✅ 6X Improvement in processing speed compared to placebo12
✅ 2.5X increase in brain growth factor (BDNF) within 60 mins so you can process information faster13
✅ 16x increase in Arc Synaptic Memory Protein, for long-term memory storage14
✅ 67% reduction in the stress hormone, corticosterone in the brain for more balanced moods15
✅ 500% increase in antioxidant enzyme activity in the brain16
✅ 49–55% reduction in 7 different inflam. markers in the brain (CRP, IL-6, TNF-α, IL-2, IL-8, MCP-1, MDA)17
Turmeric 95% Active Curcuminoids
Scientists call it “Fertilizer for the brain” because it nourishes & promotes growth of new neurons. 47x more potent than raw form turmeric found in other supplements.
✅ 28% improvement in memory over 18 months18
✅ Significant improvement in attention span19
✅ Shocking PET brain scans reveal turmeric intake results in visible reduction of “brain plaque” (amyloid and tau) the 2 proteins linked to memory decline20
→
✅ Promotes new neuron growth in hippocampus, specifically BDNF (brain-derived neurotrophic factor) and PSD95 (postsynaptic density protein 95), the two proteins critical for forming and strengthening memory connections between neurons21
Korean Ginseng
The only natural ingredient with human evidence of actually increasing gray matter volume in a memory region of the brain (the parahippocampal gyrus), proven on MRI.22
✅ 8 weeks of intake improved memory, attention and executive function for 100% of study participants23
✅ Improves immediate recall, visual memory function & 20 min delayed recall24
✅ 3.7-point improvement on the MMSE cognitive scale, the same test your doctor may perform in office to determine cognition levels25
✅ In a study of 6,422 elderly people in South Korea, those who had higher lifetime ginseng intake over five years showed higher cognitive scores compared to those who never consumed ginseng, regardless of age, gender, education, lifestyle and genotypes.)26
Reishi Mushroom
Scientifically proven to keep the brain calm under stress & reduce mental tiredness, difficulty concentrating, poor sleep & low mood.
✅ 28.3% reduction in mental fatigue27
✅ 38.7% improvement in sense of well-being28
✅ 51.6% of patients meaningfully improved vs. only 24.6% on placebo (more than 2x)29
✅ Restores the brain's key mood chemicals: serotonin and norepinephrine under stress30
✅ Physically strengthens synaptic connections between neurons, for faster recall & processing speed31
Glutathione
Researchers discovered the rate glutathione decline predicts with 100% accuracy the speed of cognitive decline.
✅ 24 weeks of Glutathione supplementation reduced oxidative stress & improved cognitive function in adults aged 70–8032
✅ In a two-year study, researchers discovered that patients experiencing memory loss showed a 46% drop in glutathione levels. Making it clear that glutathione is necessary for optimal cognitive function33
Microdose Melatonin 1mg
Scientists call it the brain's overnight cleaning system because it gently flushes out the two proteins linked to memory loss, amyloid-beta and tau (while promoting deep, uninterrupted sleep).
✅ Patients experiencing memory loss have 80% Less brain melatonin than people with healthy cognitive function34
✅ 8 randomized controlled trials involving 518 participants found that melatonin significantly improved cognitive function in adults experiencing signs of memory loss35
✅ Just 1 night of deep sleep reduces memory loss proteins in the brain. Without enough melatonin, deep restorative sleep is not possible.36
✅ Melatonin production falls 50–70% between ages 20 and 75. A 70-year-old produces roughly one-third the melatonin of a 20-year-old37
Vitamin C
Higher vitamin C levels are linked to cognitive performance across 1000s of human studies spanning more than 15 years of research.
✅ People with higher levels of vitamin C score significantly higher on immediate recall tests38
✅ In a randomization study of over 314,000 people, researchers saw higher vitamin C levels are linked to lower cognitive decline39
✅ In a study of 2,044 older adults, researchers found low vitamin C levels slowed function in the memory & attention regions of the brain40
✅ A 1 year study showed higher vitamin C levels predicted significantly slower rate of cognitive decline41
✅ Vitamin C strengthens the myelin sheath, the fatty coating on neurons that speeds up mental processing42
Selenium
Selenium is necessary for optimal brain function, yet over half of aging adults fall short43. Oral intake activates the same brain pathways as hours of intense exercise.
✅ Scientists examining brain tissue in people experiencing cognitive shifts found one consistent difference from healthy brains: significantly lower selenium levels in the exact regions responsible for memory44
✅ In a 9-year study of 1,389 adults aged 60–71, researcher discovered lower levels of selenium correlated directly with cognitive decline45
✅ In a study involving 2,416 participants aged 60+, researchers discovered higher selenium intake resulted in higher scores on three separate cognitive tests46
Zinc
In multiple clinical human studies, scientists found lower levels of zinc were directly associated with signs of cognitive decline.
✅ In clinical trials, pateints responding to zinc therapy maintained stable cognitive scores over an entire 2 year period while others continued to show signs of decline47
✅ In a study of 34,249 people, low zinc levels were associated with 34% higher chance of memory shifts with age48
✅ Researchers found zinc has the highest concentration in the brain of any organ, making it clear that the brain relies on healthy levels of zinc49
✅ In an 11 year study involving 494,632 adults, researchers found zinc supplementation was associated with a 16% reduced signs of cognitive decline50
Supplement Facts
Servings Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving
% DV
Vitamic C (as Ascorbic Acid)
200 mg | 222%
Zinc (as Glycinate)
10 mg | 91%
Selenium (as Amino Acid Chelate)
100 mcg | 182%
Proprietary Blend
1281 mg | ✝
Propolis Blend (Propolis Concentrate and Brazilian Green Propolis),
Turmeric (Curcuma longa) Rhizome Extract 95% Curcuminoids,
Korean Ginseng (Panax ginseng) Root,
Reishi Mushrooms (Ganoderma lucidem) Fruiting Body,
Glutathione,
Melatonin
✝ Daily Value not Established
Pure Neuro isn’t just “clinically backed”. It’s proven to work by some of the largest and most rigorous brain health research ever conducted…
Pure Neuro’s precision formula is based on clinical evidence from 500,000+ human participants across 70+ randomized, placebo-controlled human trials, spanning up to 12 years of follow up testing. Results have been confirmed in multiple large scale meta-analyses studies conducted globally by leading neuroscientists. The evidence behind PureNeuro’s ingredients are undeniable, including MRI and PET scans that confirm physical brain changes in participants of all ages, brain types, body types, lifestyle and genetics.
500,000+
Human Participants Of All Ages & Body Types
70+
Randomized, Placebo-Controlled Human Trials
12+ Years
Longitudinal follow
up studies by leading Neuroscientists
6+
Brain Pathways Activated, resulting in physical changes visible in MRI & PET scans
All In One Brain Support
→
PET brain imaging scans reveal oral intake of ingredients inside PureNeuro result in visible reduction of “brain plaque” (amyloid and tau) the 2 proteins linked to memory decline | American Journal of Geriatric Psychiatry51
Memory
From…
❌ Forgetting why you walked into a room
❌ Forgetting things 5 minutes after hearing them
❌ Finding yourself lost on roads you used to know like the back of your hand
❌ Watching a parent’s mind slip and wondering, “is it starting for me too?”
To…
✅ Easily recall written words, spoken conversations, lists, stories, faces and places without racking your brain or being interrupted by “senior moments”.
✅ Finally, feel confident that your long-term memories will remain intact, and secure that you and your loved ones have many more vibrant years ahead together.
What to Expect
Day 1
Day 30
Day 90
Day 365+
Day 1
Brain fog lifts and your once muddled mind becomes crystal clear, like you’re walking out of a 10-year haze.
"I noticed a difference after the first day. No more brain fog, not tired during the day."
Day 30
Words come easily again. No more forgetting names, dates, places or blanking mid conversation.
"3 weeks ago I couldn't remember one in five words. That was horrifying. Now I'm back to normal."
Day 90
Feel like YOU again: wake up so sharp, focused, alert, present and capable… it’s easy to get things done.
"After 8 months I have less brain fog, better mental sharpness and memory."
Day 365+
Transform into the sharpest, most confident version of you, no matter your age, lifestyle or family history.
"I don't go a day without it. I ran out once and could really tell a difference. So I ordered more. Can’t imagine life without PureNeuro”
"I noticed a difference after the first day. No more brain fog, not tired during the day."
11 Years Of Real Success Stories
This is why we’ve dedicated 11+ years researching, formulating and perfecting PureNeuro’s premium brain health formula. We have proudly impacted over 434,000+ families around the world. Meet just a few of 1000s of men and women of all ages and backgrounds who are now thriving thanks to Pure Neuro.
Meet the Founders
“At 49, I almost lost my Pilot’s Licence forever due to brain health. Until I took matters into my own hands”...
Hi, I’m Todd, founder of PureLife Organics. After Over 20 years of Public Service including the Army and Team Leader of SWAT running operations that protected and served millions of people, I thought I would retire and live the rest of my life with the same sharpness I always had…
I dedicated years to earning my helicopter license, so I could touch corners of the earth only few people will ever get to experience. However…
Months away from my final flight exams, my family history began to catch up with me. I could barely recall names or places. Nevermind detailed coordinates and complex flight operations.
I tried every brain supplement available, with absolutely zero progress. That’s when I contacted an elite neurological specialist who I’d met while serving in the military years earlier, and what we created together not only helped me get my pilot’s licence, but returned me to feeling the same sharp minded focus and high performance I had always known.
I had no idea then that our formula would go on to give over 434,000 other men and women their freedom back too.
Dr. Anthony Capasso, MD.
ABIM board certified Integrative medicine specialist
Globally renowned expert in preventative medicine, age management, and natural, bioidentical hormone treatment. After 25 years of practice, he dedicated 11 years of research and development to create the premium PureNeuro formula.
How does PureNeuro Stack Up?
We studied the 12 most popular brain supplements available, and we are proud to say PureNeuro consistently outranks all of them. We have created the one and only natural formula with ingredients scientifically documented to support both cognitive performance and protection through 6+ unique brain pathways, all in 1 convenient, caffeine-free capsule.
Scientifically Documented Research ⬇️
Memory loss protein defense
Long-term memory storage
Mental stress resistance
Mitochondrial support
Neurotransmitter communication
Neurogenesis (New brain cell growth)
500,000+ person research base
70+ randomized controlled trials
Cumulative long-term benefits
Prevagen
Neuriva
Alpha Brain
Mind Lab Pro
Qualia Mind
Other Brands
Sometimes
Sometimes
Sometimes
Pure Neuro
Frequently Asked Questions
How much Pure Neuro should I take?
This is pretty easy. Take 2 capsules daily after your evening meal.
How long should I take Pure Neuro?
Most people begin noticing a difference within 2 weeks. However, since Pure Neuro is designed to renew and reinforce the Mitochondria that supply the brain with the Cellular Energy it needs to work at its best, you should continue taking Pure Neuro for as long as you can. Dr Capasso recommends at least 3 months to provide a solid boost to your brain power, or 6 months to have the best shot at rebuilding impressive Cellular Energy.
Is Pure Neuro a stimulant or a drug?
Pure Neuro is not in any way a stimulant or drug. The formulation created by Dr Capasso is a blend of natural nutrients only.
Will Pure Neuro interfere with other supplements or pharmaceuticals?
We have not received any reports of Pure Neuro interfering with any other supplements or prescriptions. However it is always important to consult with your doctor before adding any new supplement to your routine.
Are there any side effects with Pure Neuro?
The natural ingredients inside Pure Neuro are not associated with side effects. And we have not received any reports of Pure Neuro causing side effects for our customers. However it is always important to consult with your doctor before adding any new supplement to your routine.
How does Pure Neuro work again?
Dr Capasso carefully formulated Pure Neuro to support the protective effect of the Blood Brain Barrier, while simultaneously restoring Cellular Energy to the brain cells by nourishing the brain’s Mitochondria. Since each thought or memory we have is like a special pattern of electricity. When the brain’s energy supply gets low it can make us forget things or feel confused. Pure Neuro restores the Cellular Energy we need for youthful memory and focus.
Reviewed & Recommended
⭐⭐⭐⭐⭐ 4.8/5 Trusted by 434,000+ customers
✔️ Focus. Clarity. Memory. Mood. Holistic Brain Health.
✔️ World’s first 100% natural & premium brain supplement backed by 70+ randomized placebo-controlled trials involving 500,000+ people
✔️ 100% natural, premium & clean formula, third party tested for purity
✔️ Caffiene & stimulant free
✔️ 60 day guarantee
⭐ Providing world class customer service
⭐⭐⭐⭐⭐ 4.8/5 Trusted by 434,000+ men and women
References
1 Double-blind, human, placebo-controlled Randomized Controlled Trial | Asama et al., Evidence-Based Complementary and Alternative Medicine, 2021
2 Double-blind, human, placebo-controlled Randomized Controlled Trial | Asama et al., Evidence-Based Complementary and Alternative Medicine, 2021
3 In vitro cell study | Human neuronal SH-SY5Y cells | Oxidative Medicine and Cellular Longevity, 2017 | Ni, Wu, Meng et al.
4 In vitro cell study | Human neuronal SH-SY5Y cells | Oxidative Medicine and Cellular Longevity, 2017 | Ni, Wu, Meng et al.
5 In vitro cell study | Human neuronal SH-SY5Y cells | Oxidative Medicine and Cellular Longevity, 2017 | Ni, Wu, Meng et al.
6 In vitro cell study | Human neuronal SH-SY5Y cells | Oxidative Medicine and Cellular Longevity, 2017 | Ni, Wu, Meng et al.
7 Double-blind, human, placebo-controlled Randomized Controlled Trial | Asama et al., Evidence-Based Complementary and Alternative Medicine, 2021
8 Double-blind, human, placebo-controlled Randomized Controlled Trial | Asama et al., Evidence-Based Complementary and Alternative Medicine, 2021
11 Double-blind, human, placebo-controlled Randomized Controlled Trial | Asama et al., Evidence-Based Complementary and Alternative Medicine, 2021
12 Double-blind, human, placebo-controlled Randomized Controlled Trial | Asama et al., Evidence-Based Complementary and Alternative Medicine, 2021
13 In vitro cell study | Human neuronal SH-SY5Y cells | Oxidative Medicine and Cellular Longevity, 2017 | Ni, Wu, Meng et al.
14 In vitro cell study | Human neuronal SH-SY5Y cells | Oxidative Medicine and Cellular Longevity, 2017 | Ni, Wu, Meng et al.
15 Journal of Pharmacy and Pharmacology, 2023 | Celebi et al.
16 Journal of Pharmacy and Pharmacology, 2023 | Celebi et al.
17 Systematic Review & Meta-Analysis of 27 Randomized Control Trials Frontiers in Nutrition, May 2025 | Bahari et al.
18 Double-blind, placebo-controlled Randomized Controlled Trial | Small et al., American Journal of Geriatric Psychiatry, 2018
19 Double-blind, placebo-controlled Randomized Controlled Trial | Small et al., American Journal of Geriatric Psychiatry, 2018
20 Double-blind, placebo-controlled Randomized Controlled Trial | Small et al., American Journal of Geriatric Psychiatry, 2018
21 Nature Scientific Reports, Neurogenesis Study on cognitive deficit reversal | Li, Wu, Wang et al. China Academy of Chinese Medical Sciences, 2025
22 The Brain Volume Double-blind, placebo-controlled Randomized Trial | Namgung et al., Human Psychopharmacology, 2021
23 The Brain Volume Double-blind, placebo-controlled Randomized Trial | Namgung et al., Human Psychopharmacology, 2021
24 Double-blind, placebo-controlled RCT 90 participants with Mild Cognitive Impairment 6 months | Park et al., Translational and Clinical Pharmacology, 2019
25 Meta-Analysis of 15 randomized Control Trials 671 Participants | Phytotherapy Research, Zeng et al. 2004
26 Large observational cohort study 6,422 elderly Koreans | Alzheimer's Research & Therapy, Rami Lee, Ji-Hun Kim et al. 2018
27 Double-blind, placebo-controlled randomized control trial 132 patients 8 weeks | Journal of Medicinal Food, Tang, Gao, Chen et al. 2005
28 Double-blind, placebo-controlled randomized control trial 132 patients 8 weeks | Journal of Medicinal Food, Tang, Gao, Chen et al. 2005
29 Double-blind, placebo-controlled randomized control trial 132 patients 8 weeks | Journal of Medicinal Food, Tang, Gao, Chen et al. 2005
30 Double-blind, placebo-controlled randomized control trial 132 patients 8 weeks | Journal of Medicinal Food, Tang, Gao, Chen et al. 2005
31 Double-blind, placebo-controlled randomized control trial 132 patients 8 weeks | Journal of Medicinal Food, Tang, Gao, Chen et al. 2005
32https://pubmed.ncbi.nlm.nih.gov/33783984/
33https://pmc.ncbi.nlm.nih.gov/articles/PMC8615204/
34https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771063/
35https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726096/
36https://pmc.ncbi.nlm.nih.gov/articles/PMC12366049/
37https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771063/
38https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2019.00072/full
39https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555275/
40https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0348504
41https://lpi.oregonstate.edu/mic/vitamins/vitamin-C
42https://www.psychologytoday.com/ca/articles/201801/the-cognitive-benefits-vitamin-c
43https://pmc.ncbi.nlm.nih.gov/articles/PMC7251157/
44https://link.springer.com/article/10.1007/s12011-018-1492-x
45https://www.sciencedirect.com/science/article/pii/S0261561425001232
46https://www.nature.com/articles/s41598-024-75652-2
47 Meta-Analysis of 15 randomized Control Trials 671 Participants | Phytotherapy Research, Zeng et al. 2004
48https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1666887/full
49https://pmc.ncbi.nlm.nih.gov/articles/PMC9448499/
50https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10794302/
51 Double-blind, placebo-controlled Randomized Controlled Trial | Small et al., American Journal of Geriatric Psychiatry, 2018
52https://pmc.ncbi.nlm.nih.gov/articles/PMC6272892/